---
title: "Duplifense - s&box game"
description: "Duplifense is a strategic tower defense game where you must protect your weapon factory from waves of enemies."
canonical: "https://sbox.watch/games/tinyotter/duplifense/"
generated_at: "2026-07-23T00:21:26.397Z"
---

# Duplifense

Duplifense is a strategic tower defense game where you must protect your weapon factory from waves of enemies.

- Type: game
- Ident: tinyotter.duplifense
- Creator: Tiny Otter
- Canonical: https://sbox.watch/games/tinyotter/duplifense/
- Markdown: https://sbox.watch/games/tinyotter/duplifense.md
- sbox.game: https://sbox.game/tinyotter/duplifense/
- Generated: 2026-07-23T00:21:26.397Z

## Stats

- Playing now: 0
- 24h player peak: 0
- 24h momentum: +0
- Terry score: 78%
- Favorites: 129
- Upvotes: 97
- Downvotes: 18
- Total players: 739
- Total sessions: 957
- Cumulative playtime: 9.3 days
- Updated: Apr 28, 2026
- Created: Jun 26, 2025
- Size: 63.5 MB
- Files: 808
- Tags: copy, defence, defense, duplicate, replicate, tower

## Description

Duplifense — Tower Defense with Mutations

Duplifense is a tower defense game where you protect your copying factory from waves of enemies.

Blueprints:
To make towers, you need blueprints and parts dropped by enemies. Not all tower blueprints are available from start, you can:
- Get new blueprints from bosses
- Research a tower

All blueprints are saved between sessions.

Mutations:
A mutation is a random change that gives a tower different stats. If you study a mutated tower, you unlock a new blueprint based on it.

The more you mutate and study, the more powerful towers you can build. But crafting takes time, so you must plan carefully: build, upgrade, and defend your factory before the enemies break through!

Additional Info:
 ​We recommend using the stable branch of s&box for a better experience.

Controls:
\[WASD\] - Movement
Hold \[MMB\] and move mouse for movement
\[Scroll\] - Zoom
\[RMB\] - Rotation
\[Tab\] - Inventory
\[C\] - Craft or take the tower

Q&A:
- Too easy? Did you get to the 100th wave in last level? No? Then don't tell me it's easy.
- "Crafting and resources are a bit unnecessary" - try getting to 100th wave with default blueprints